Betaine For Nonalcoholic Fatty Liver Disease: Results Of A Randomized Placebo-controlled Trial
効果 | なし |
試験方法 | 二重盲検法 |
試験期間 | 6+ Months |
被験者数 | 34 |
性別 | 男女 |
年齢 | 30-44, 45-64, 65+ |
体型 | 肥満 |
Supplementation of 10g betaine twice daily for one year in persons with nonalcoholic fatty liver disease was able to increase methionine and SAMe levels, but did not reduce S-adenosylhomocysteine levels. Alongside this, there were failures to reduce liver enzymes or fibrotic scores, although liver fat (steatosis) was reduced with betaine and the progression of the disease state was lower in betaine relative to placebo.
General symptoms and well being was not different between groups.
Betaine Supplementation Decreases Plasma Homocysteine Concentrations But Does Not Affect Body Weight, Body Composition, Or Resting Energy Expenditure In Human Subjects
効果 | なし |
試験方法 | 二重盲検法 |
試験期間 | 6+ Months |
被験者数 | 42 |
性別 | 男女 |
年齢 | 18-29, 30-44 |
体型 | 肥満 |
In obese subjects given supplementation of betaine at 6g daily for 12 weeks was able to decrease homocysteine (9%) relative to placebo but the decrease in total cholesterol and LDL seen in placebo was not present in betaine intervention; there was no influence on body weight. There was no influence on plasma nor RBC folate concentrations.
The increase in ALP (liver enzyme) seen in placebo was prevented with betaine.
Effect Of Betaine Supplementation On Cycling Sprint Performance
効果 | なし |
試験方法 | 二重盲検法 |
試験期間 | 1-2 週間 |
被験者数 | 16 |
性別 | 男女 |
年齢 | 18-29 |
体型 | トレーニング中, 平均 |
Oral supplementation of betaine at 2.5g daily over the course of two weeks appears to increase average (3.4%) and maximum (3.8%) peak power output on a cycling test (four 12s sprints against resistance) as well as average (3.3%) and peak (3.5%) mean power output relative to placebo
Funded by Dupont Nutrition
Creatine But Not Betaine Supplementation Increases Muscle Phosphorylcreatine Content And Strength Performance
効果 | なし |
試験方法 | 二重盲検法 |
試験期間 | 1-2 週間 |
被験者数 | 34 |
性別 | 男性 |
年齢 | 18-29 |
体型 | トレーニングしてない, 平均 |
Supplementation of 2g betaine over the course of 10 days to otherwise healthy adult men (sedentary) failed to increase phosphocreatine content in muscle tissue and failed to augment the creatine induced increase when 2g of betaine was added to 20g creatine.