Betaine For Nonalcoholic Fatty Liver Disease: Results Of A Randomized Placebo-controlled Trial
| 効果 | なし |
| 試験方法 | 二重盲検法 |
| 試験期間 | 6+ Months |
| 被験者数 | 34 |
| 性別 | 男女 |
| 年齢 | 30-44, 45-64, 65+ |
| 体型 | 肥満 |
この研究の注釈：
Supplementation of 10g betaine twice daily for one year in persons with nonalcoholic fatty liver disease was able to increase methionine and SAMe levels, but did not reduce S-adenosylhomocysteine levels. Alongside this, there were failures to reduce liver enzymes or fibrotic scores, although liver fat (steatosis) was reduced with betaine and the progression of the disease state was lower in betaine relative to placebo.
Supplementation of 10g betaine twice daily for one year in persons with nonalcoholic fatty liver disease was able to increase methionine and SAMe levels, but did not reduce S-adenosylhomocysteine levels. Alongside this, there were failures to reduce liver enzymes or fibrotic scores, although liver fat (steatosis) was reduced with betaine and the progression of the disease state was lower in betaine relative to placebo.
General symptoms and well being was not different between groups.