| 効果 | なし |
| 試験方法 | 二重盲検法 |
| 試験期間 | 1-7 日 |
| 被験者数 | 150 |
| 性別 | 男女 |
| 年齢 | 18-29, 30-44, 45-64 |
| 体型 | 肥満, 平均 |
Relative to the comparator drugs (betamethasone and paracetamol), serrapeptase was less effective in reducing pain and inflammation associated with third molar surgery when taken at the standard 30mg dosage; relative to placebo, there was no significant difference.
Comparison Of The Roles Of Serratiopeptidase And Dexamethasone In The Control Of Inflammation And Trismus Following Impacted Third Molar Surgery
| 効果 | 減少 |
| 試験方法 | 二重盲検法 |
| 試験期間 | 1-7 日 |
| 被験者数 | 110 |
| 性別 | 男女 |
| 年齢 | 18-29, 30-44, 45-64, 65+ |
| 体型 | 肥満, 平均 |
In patients undergoing jaw surgery (removal of third molar), 30mg serrapeptase daily for up to a week was more effective than placebo in reducing pain and swelling although trismus (opening of the jaw) was unaffected.
Reduction Of Postoperative Swelling. Objective Measurement Of Swelling Of The Upper Ankle Joint In Treatment With Serrapeptase– A Prospective Study
| 効果 | 減少 |
| 試験方法 | コホート法 |
| 試験期間 | 不明 |
| 被験者数 | 66 |
| 性別 | 男女 |
In persons with Postoperative and traumatic swelling (knee surgery) given serrapeptase (dose not specified) or a control group of ice and bed rest noted that in the serrapeptase group swelling was reduced by 50% on day 5 and eliminated on day 10. No indication that any placebo controlling was utilized, although randomization was specified
A Multi-centre, Double-blind Study Of Serrapeptase Versus Placebo In Post-antrotomy Buccal Swelling
| 効果 | 減少 |
| 試験方法 | 二重盲検法 |
| 試験期間 | 1-7 日 |
| 被験者数 | 174 |
| 性別 | 男女 |
| 年齢 | 18-29, 30-44, 45-64 |
In persons given serrapeptase at 30mg (10mg thrice daily) for 7 days after surgery (Caldwell-luc antrotomy) in order to assess buccal swelling noted that the serrapeptase group outperformed placebo in reducing swelling associated with surgery.