| 効果 | 減少 |
| 試験方法 | 二重盲検法 |
| 試験期間 | 1-6 ヶ月 |
| 被験者数 | 110 |
| 性別 | 女性 |
| 年齢 | 30-44, 45-64, 65+ |
| 体型 | 平均 |
この研究の注釈：
12 weeks supplementation of a _ruscus aculeatus_ extract at 36-37.5mg of a 15-20:1 concentration in women with chronic venous insufficiency was able to reduce lower limb circumference (anti-edemic actions in the leg and ankles) while improving global symptoms of CVI, although it did not have any efficacy on quality of life relative to placebo.