| 効果 | 減少 |
| 試験方法 | 二重盲検法 |
| 試験期間 | 1-6 ヶ月 |
| 被験者数 | 35 |
| 性別 | 男女 |
| 年齢 | 18-29, 30-44, 45-64 |
| 体型 | 平均 |
この研究の注釈：
In persons with primary grade 1 osteoarthritic symptoms, supplementation of pycnogenol at 50mg thrice daily was noted to, over the course of 90 days, reduce pain and functional impairment associated with osteoarthritis in the range of 35-52% (depending on what was being measured). It took 90 days for this magnitude of benefit to be see, and although all but stiffness benefitted slightly by 60 days there was no effect on day 30.