pycnogenol-ldl-c

この研究の注釈：

150mg Pycnogenol daily for 6 weeks was associated with a reduction of LDL for as long as supplementation was maintained and was associated with an improvment in antioxidant status; HDL was also increased, but remained increased after 4 weeks supplement cessation.

この研究の注釈：

Supplementation of 125mg pycnogenol daily for 12 weeks in type II diabetics currently on ACE inhibitor therapy showed benefits to blood pressure in 58.3% of subjects by halving their required dosage of ACE inhibitor. Other biomarkers, such as endothelin-1, glucose, and HbA1c all decreased relative to placebo.

A reduction in urinary albumin was noted after two months but this may have reached significance due to a spike in the placebo group, both groups normalized within three months of supplementation and there was no significant differences at this time.

Most effects required two months of supplementation to manifest, maintaining in potency for the third month and not occurring within the first.

研究の資金源に関する問題点：

Study funded by Horphag research, producers of pycnogenol supplements

この研究の注釈：

A comparative study between chestnut seed extract and Pycnogenol found that the latter was associated with a reduction in LDL-C and TC, but not HDL-C, over 4 weeks with 360mg. Decreased venous insufficiency symptoms and leg swelling was also noted.