N-acetylcysteine Add-on Treatment In Refractory Obsessive-compulsive Disorder: A Randomized, Double-blind, Placebo-controlled Trial

効果 減少
試験方法 二重盲検法
試験期間 1-6 ヶ月
被験者数 48
性別 男女
年齢 18-29, 30-44
体型 平均
この研究の注釈：

12 weeks supplementation of N-acetylcysteine up to 2,400mg daily in persons with OCD who were being mediated (with SRIs) but were unresponsive to said mediciation noted that the response rate in reducing symptoms of OCD rose from 15% in placebo to 52.6% in the NAC group (a ‘response’ being a 35% reduction in symptoms or more); this is thought to be due to NAC being able to reverse or attenuate resistance to SRI therapy.