| 効果 | 減少 |
| 試験方法 | 二重盲検法 |
| 試験期間 | 1-6 ヶ月 |
| 被験者数 | 31 |
| 性別 | 男女 |
| 年齢 | 1-6, 7-12, 13-17 |
この研究の注釈：
Eight weeks supplementation of NAC as adjuvant to risperidone therapy in children with autism was able to reduce irritability relative to placebo, but the other measured parameters (Lethargy and Social Withdrawal, Stereotypic Behavior, Hyperactivity, and Noncompliance) were not affected by treatment.
A Randomized Controlled Pilot Trial Of Oral N-acetylcysteine In Children With Autism
| 効果 | 減少 |
| 試験方法 | 二重盲検法 |
| 試験期間 | 1-6 ヶ月 |
| 被験者数 | 25 |
| 性別 | 男女 |
| 年齢 | 1-6, 7-12 |
この研究の注釈：
Although there was a reduction in irritability in persons with autism when taking N-acetylcysteine (900mg for four weeks, 1,800mg for another four, an 2,700mg for the final four weeks) relative to placebo, all other parameters of autism as assessed by multiple rating scales (SRS, RBS, ABC) were not significantly affected.
