Treatment Of Hirsutism With Myo-inositol: A Prospective Clinical Study
| 効果 | なし |
| 試験方法 | コホート法 |
| 試験期間 | 6+ ヶ月 |
| 被験者数 | 46 |
| 性別 | 女性 |
| 年齢 | 18-29 |
| 体型 | 肥満 |
6 months of treatment with 2g inositol to women with hirsutism was associated with reductions in the symptoms directly as well as improvements in insulin sensitivity.
The Combined Therapy With Myo-inositol And D-chiro-inositol Reduces The Risk Of Metabolic Disease In PCOS Overweight Patients Compared To Myo-inositol Supplementation Alone
| 効果 | 減少 |
| 試験方法 | コホート法 |
| 試験期間 | 6+ ヶ月 |
| 被験者数 | 50 |
| 性別 | 女性 |
| 年齢 | 18-29, 30-44 |
| 体型 | 肥満 |
Supplementation of myo-inositol by itself at 2g daily for a period of six months in women with PCOS was associated with improvements in diastolic blood pressure. The combination with D-chiroinositol was the same at a lower dose (550mg and 13.8mg, respectively) when measured at six months, but seemed to act faster as inositol at 2g required six months to be fully effective.
Effects Of Inositol On Ovarian Function And Metabolic Factors In Women With PCOS: A Randomized Double Blind Placebo-controlled Trial
| 効果 | なし |
| 試験方法 | 二重盲検法 |
| 試験期間 | 1-6 ヶ月 |
| 被験者数 | 281 |
| 性別 | 女性 |
| 年齢 | 18-29, 30-44 |
| 体型 | 肥満 |
200mg of inositol daily (in two divided doses of 100mg) for a period of 12 weeks in women with PCOS was ineffective in improving the glucose metabolic markers yet was effective in reducing body weight and improving fertility.
Efficacy Of Myo-inositol In The Treatment Of Cutaneous Disorders In Young Women With Polycystic Ovary Syndrome
| 効果 | 減少 |
| 試験方法 | コホート法 |
| 試験期間 | 1-6 ヶ月 |
| 被験者数 | 50 |
| 性別 | 女性 |
| 年齢 | 30-44 |
| 体型 | 平均 |
Supplementation of inositol in young women with PCOS (of which hirstuism and acne are common side effects) was therapeutic over the course of six months of treatment at 2,000mg.
Acne at baseline was either moderate (68%) or severe (32%) and, after supplementation, it was reduced respectively to 34% and 13% with more than half the sample (53%) noting an abolishment of all acne.
No placebo control group was used.
One-year Effects Of Myo-inositol Supplementation In Postmenopausal Women With Metabolic Syndrome
| 効果 | 減少 |
| 試験方法 | 二重盲検法 |
| 試験期間 | 6+ ヶ月 |
| 被験者数 | 80 |
| 性別 | 女性 |
| 年齢 | 45-64, 65+ |
| 体型 | 肥満 |
Supplementation of myo-inositol at 2g twice daily for the course of one year in postmenopausal women with metabolic syndrome was associated with improvements on all metabolic parameters measured (cardiovascular health and glucose metabolism) although no influence on weight was noted.
Inositol Administration Reduces Oxidative Stress In Erythrocytes Of Patients With Polycystic Ovary Syndrome
| 効果 | 減少 |
| 試験方法 | 二重盲検法 |
| 試験期間 | 1-6 ヶ月 |
| 被験者数 | 26 |
| 性別 | 女性 |
| 年齢 | 18-29 |
| 体型 | 平均 |
Supplementation of 1,200mg Myo-inositol daily for a period of 12 weeks in normal weight women (22-30yrs) with PCOS was able to decrease weight (−1.83+/-1.86kg, very unreliable in magnitude) and improved markers of glucose and androgen metabolism. An improvement in oxidative biomarkers was also noted (GSH in red blood cells).
Differential Insulin Response To Myo-inositol Administration In Obese Polycystic Ovary Syndrome Patients
| 効果 | 減少 |
| 試験方法 | コホート法 |
| 試験期間 | 1-6 ヶ月 |
| 被験者数 | 42 |
| 性別 | 女性 |
| 年齢 | 18-29, 30-44 |
| 体型 | 肥満 |
Supplementation of 2,000mg inositol (INOFERT) once daily for eight weeks in obese women with PCOS was able to improve insulin sensitivity and other biomarkers of glucose metabolism only in those with higher circulating insulin concentrations.
No placebo control was used in this study.