inositol-insulin-sensitivity

この研究の注釈：

6 months of treatment with 2g inositol to women with hirsutism was associated with reductions in the symptoms directly as well as improvements in insulin sensitivity.

この研究の注釈：

Supplementation of myo-inositol by itself at 2g daily for a period of six months in women with PCOS was associated with improvements in diastolic blood pressure. The combination with D-chiroinositol was the same at a lower dose (550mg and 13.8mg, respectively) when measured at six months, but seemed to act faster as inositol at 2g required six months to be fully effective.

この研究の注釈：

200mg of inositol daily (in two divided doses of 100mg) for a period of 12 weeks in women with PCOS was ineffective in improving the glucose metabolic markers yet was effective in reducing body weight and improving fertility.

この研究の注釈：

Supplementation of 4,000mg inositol daily during pregnancy in otherwise healthy women significantly reduced the decline in insulin sensitivity associated with the third trimester of pregnancy.

この研究の注釈：

6-8 weeks of supplementation with 600mg D-chiro-inositol daily in women with PCOS who also had an average BMI was able to increase ovulation secondary to reducing androgens, and appears to be effective in improving other biomarkers of health such as blood pressure and triglycerides.

この研究の注釈：

Supplementation of inositol in young women with PCOS (of which hirstuism and acne are common side effects) was therapeutic over the course of six months of treatment at 2,000mg.

Acne at baseline was either moderate (68%) or severe (32%) and, after supplementation, it was reduced respectively to 34% and 13% with more than half the sample (53%) noting an abolishment of all acne.

No placebo control group was used.

この研究の注釈：

Supplementation of 4,000mg inositol daily for a period of 12-16 weeks in women with PCOS was able to improve tolerance to glucose and glucose handling (as well as reduce the amount of insulin secreted in response to a meal) with minor benefits to cardiovascular health as well.

この研究の注釈：

2,000mg inositol daily in overweight women with PCOS

この研究の注釈：

Supplementation of myo-inositol at 2g twice daily for the course of one year in postmenopausal women with metabolic syndrome was associated with improvements on all metabolic parameters measured (cardiovascular health and glucose metabolism) although no influence on weight was noted.

この研究の注釈：

Supplementation of 1,200mg Myo-inositol daily for a period of 12 weeks in normal weight women (22-30yrs) with PCOS was able to decrease weight (−1.83+/-1.86kg, very unreliable in magnitude) and improved markers of glucose and androgen metabolism. An improvement in oxidative biomarkers was also noted (GSH in red blood cells).

この研究の注釈：

4g of inositol daily for a period of 16 weeks in women with PCOS was ineffective in improving parameters of insulin sensitivity while it was sufficient to improve biomarkers of steroid metabolism and fertility. Weight was decreased in all subjects who were not morbidly obese.

この研究の注釈：

Supplementation of 2,000mg inositol (INOFERT) once daily for eight weeks in obese women with PCOS was able to improve insulin sensitivity and other biomarkers of glucose metabolism only in those with higher circulating insulin concentrations.

No placebo control was used in this study.