Treatment Of Hirsutism With Myo-inositol: A Prospective Clinical Study
| 効果 | 増加 |
| 試験方法 | コホート法 |
| 試験期間 | 6+ ヶ月 |
| 被験者数 | 46 |
| 性別 | 女性 |
| 年齢 | 18-29 |
| 体型 | 肥満 |
6 months of treatment with 2g inositol to women with hirsutism was associated with reductions in the symptoms directly as well as improvements in insulin sensitivity.
Effects Of Inositol On Ovarian Function And Metabolic Factors In Women With PCOS: A Randomized Double Blind Placebo-controlled Trial
| 効果 | 増加 |
| 試験方法 | 二重盲検法 |
| 試験期間 | 1-6 ヶ月 |
| 被験者数 | 281 |
| 性別 | 女性 |
| 年齢 | 18-29, 30-44 |
| 体型 | 肥満 |
200mg of inositol daily (in two divided doses of 100mg) for a period of 12 weeks in women with PCOS was ineffective in improving the glucose metabolic markers yet was effective in reducing body weight and improving fertility.
One-year Effects Of Myo-inositol Supplementation In Postmenopausal Women With Metabolic Syndrome
| 効果 | 増加 |
| 試験方法 | 二重盲検法 |
| 試験期間 | 6+ ヶ月 |
| 被験者数 | 80 |
| 性別 | 女性 |
| 年齢 | 45-64, 65+ |
| 体型 | 肥満 |
Supplementation of myo-inositol at 2g twice daily for the course of one year in postmenopausal women with metabolic syndrome was associated with improvements on all metabolic parameters measured (cardiovascular health and glucose metabolism) although no influence on weight was noted.
Randomized, Double Blind Placebo-controlled Trial: Effects Of Myo-inositol On Ovarian Function And Metabolic Factors In Women With PCOS
| 効果 | 増加 |
| 試験方法 | 二重盲検法 |
| 試験期間 | 1-6 ヶ月 |
| 被験者数 | 92 |
| 性別 | 女性 |
| 年齢 | 18-29, 30-44 |
| 体型 | 肥満, 肥満, 平均 |
4g of inositol daily for a period of 16 weeks in women with PCOS was ineffective in improving parameters of insulin sensitivity while it was sufficient to improve biomarkers of steroid metabolism and fertility. Weight was decreased in all subjects who were not morbidly obese.
Myo-inositol Treatment Increases Serum Plasmalogens And Decreases Small Dense LDL, Particularly In Hyperlipidemic Subjects With Metabolic Syndrome
| 効果 | なし |
| 試験方法 | コホート法 |
| 試験期間 | 1-2 週間 |
| 被験者数 | 17 |
| 性別 | 男女 |
| 年齢 | 30-44, 45-64 |
| 体型 | 肥満 |
Two weeks supplementation of _myo_-inositol at 5g (first week) and 10g (second week) was able to increase circulating levels of choline plasmalogen, which is thought to be the reason behind a reduction in LDL-C. These changes were not present in persons without metabolic syndrome.