inositol-depression

この研究の注釈：

Supplementation of 12g inositol daily for a period of six weeks in persons with bipolar disorder and depression was associated with a trend towards reducing symptoms of bipolar disorder and depressive symptoms, but this was not statistically significant.

この研究の注釈：

In an open-label trial, depressive symptoms of bipolar disorder were significantly reduced in response to inositol supplementation over six weeks. No placebo control was used in this study.

この研究の注釈：

Over the course of six menstrual cycles, supplementation with 12g inositol or its gel form equivalent (3.6g) were both effective in reducing dysphoria and depression associated with PMS.

この研究の注釈：

Supplementation of 12g inositol daily for a period of four weeks to depressed persons was associated with significant improvements in depressive symptoms. Treatment was well tolerated.

この研究の注釈：

Supplementation of 12g inositol over the course of four weeks in persons who were nonresponsive to 3 weeks of SSRI therapy failed to outperform placebo in reducing depressive symptoms.

この研究の注釈：

Supplementation of 18g inositol in persons with binge eating disorder or bulimia was effective in reducing symptoms of binge eating as well as both anxiety and depression.

The lone male patient did not respond to treatment.

この研究の注釈：

In a placebo controlled crossover design, supplementation of 18g inositol daily for six weeks in persons with obsessive compulsive disorder was able to reduce symptoms as assessed by the Yale-Brown Obsessive Compulsive Scale (to 76% of baseline; placebo down to 94%)

この研究の注釈：

Supplementation of 6g inositol to treatment resistant depressed persons was able to improve depressive symptoms in 9/11 persons (open-label trial) and a subsequent double-blind trial in schizophrenic persons failed to find any apparent benefit over 30 days with the same dose.

Liver and kidney function was unaffected.