| 効果 | なし |
| 試験方法 | 二重盲検法 |
| 試験期間 | 1-6 ヶ月 |
| 被験者数 | 31 |
| 性別 | 女性 |
| 年齢 | 45-64, 65+ |
| 体型 | トレーニングしてない, 肥満 |
この研究の注釈：
50mg of DHEA over 12 weeks in healthy postmenopausal women with an average age of 64.6yrs and who were sedentary at the start of the study.
50mg of DHEA over 12 weeks in healthy postmenopausal women with an average age of 64.6yrs and who were sedentary at the start of the study.
With the introduction of exercise, beneficial changes in body composition were due to exercise and there was no difference in the DHEA group relative to placebo.
A reduction in small dense LDL particles (oxidized LDL usually) was noted.
研究の資金源に関する問題点：
NIH grant, likely a nonissue
Short-term Dehydroepiandrosterone Treatment Increases Platelet CGMP Production In Elderly Male Subjects
| 効果 | なし |
| 試験方法 | 二重盲検法 |
| 試験期間 | 1-6 ヶ月 |
| 被験者数 | 24 |
| 性別 | 男性 |
| 年齢 | 45-64, 65+ |
| 体型 | 肥満, 平均 |
この研究の注釈：
2 months of DHEA supplements, 50mg at bedtime, was able to increase circulating levels of Platelet cyclic guanosine-monophosphate, a biomarker for Nitric Oxide.
2 months of DHEA supplements, 50mg at bedtime, was able to increase circulating levels of Platelet cyclic guanosine-monophosphate, a biomarker for Nitric Oxide.
It increased testosterone and estrogen, as well as plasminogen activating factor-1. Interestingly, DHEA also lowered LDL. Other biomarkers measured were not significantly affected.
Oral Dehydroepiandrosterone Replacement In Older Adults: Effects On Central Adiposity, Glucose Metabolism And Blood Lipids
| 効果 | 減少 |
| 試験方法 | 二重盲検法 |
| 試験期間 | 不明 |
| 被験者数 | 118 |
| 性別 | 不明 |
この研究の注釈：
50mg of DHEA take daily for 1 year in otherwise healthy but aged individuals of both genders was able to reduce fasting triglycerides and HDL-C, but was unable to influence other measured parameters and body composition.