| 効果 | 増加 |
| 試験方法 | コホート法 |
| 試験期間 | 6+ ヶ月 |
| 被験者数 | 20 |
| 性別 | 女性 |
| 年齢 | 45-64 |
| 体型 | 肥満 |
この研究の注釈：
25mg of DHEA over 12 months was able to increase all steroid hormones in the serum, including the neurosteroids allopregnanolone and beta-endorphin. SHBG also decreased alongside cortisol, and overall menopausal symptoms in these women was decreased.
Six-month Oral Dehydroepiandrosterone Supplementation In Early And Late Postmenopause
| 効果 | なし |
| 試験方法 | 二重盲検法 |
| 試験期間 | 1-6 ヶ月 |
| 被験者数 | 36 |
| 性別 | 女性 |
| 年齢 | 45-64 |
| 体型 | 肥満, 平均 |
この研究の注釈：
50mg of DHEA over 6 months in menopausal women showed that testosterone and estrogen increased, while SHBG decreased only in overweight women significantly. Plasma levels of neurosteroids (beta-endorphin and allopregnanolone) increased while cortisol and gonadotropins decreased.
50mg of DHEA over 6 months in menopausal women showed that testosterone and estrogen increased, while SHBG decreased only in overweight women significantly. Plasma levels of neurosteroids (beta-endorphin and allopregnanolone) increased while cortisol and gonadotropins decreased.
SHBG decreased only in the subset of postmenopausal women who were older and overweight.