Dehydroepiandrosterone Supplementation Improves Endothelial Function And Insulin Sensitivity In Men
| 効果 | 減少 |
| 試験方法 | 二重盲検法 |
| 試験期間 | 不明 |
| 被験者数 | 24 |
| 性別 | 不明 |
In older men with hypercholesterolemia (average age 54), 25mg DHEA daily was able to increaes blood flow and improve endothelial function while decreasing blood glucose (no influence on plasma insulin)
Dehydroepiandrosterone Replacement In Healthy Men With Age-related Decline Of DHEA-S: Effects On Fat Distribution, Insulin Sensitivity And Lipid Metabolism
| 効果 | なし |
| 試験方法 | 二重盲検法 |
| 試験期間 | 1-6 ヶ月 |
| 被験者数 | 12 |
| 性別 | 男性 |
| 年齢 | 45-64 |
| 体型 | 肥満 |
50mg of DHEA given for 3 months in a double blind manner to aged men with low circulating DHEA levels but otherwise healthy status was unable to significantly influence any study parameter despite increasing circulating DHEA levels. The only effect that was notable was an increasing trend to increase LDL and Triglycerides, which did not reach statistical significance.
Short-term Dehydroepiandrosterone Treatment Increases Platelet CGMP Production In Elderly Male Subjects
| 効果 | なし |
| 試験方法 | 二重盲検法 |
| 試験期間 | 1-6 ヶ月 |
| 被験者数 | 24 |
| 性別 | 男性 |
| 年齢 | 45-64, 65+ |
| 体型 | 肥満, 平均 |
2 months of DHEA supplements, 50mg at bedtime, was able to increase circulating levels of Platelet cyclic guanosine-monophosphate, a biomarker for Nitric Oxide.
It increased testosterone and estrogen, as well as plasminogen activating factor-1. Interestingly, DHEA also lowered LDL. Other biomarkers measured were not significantly affected.