Creatine Supplementation In Parkinson Disease: A Placebo-controlled Randomized Pilot Trial
| 効果 | なし |
| 試験方法 | 二重盲検法 |
| 試験期間 | 6+ Months |
| 被験者数 | 60 |
| 性別 | 男女 |
| 年齢 | 65+ |
| 体型 | 肥満 |
この研究の注釈：
2 year trial of creatine monohydrate supplementation on Parkinson’s Disease.
2 year trial of creatine monohydrate supplementation on Parkinson’s Disease.
Improvements in mood noted, but no improvements on parameters of Parkinson’s disease (as measured by the Unified Parkinson’s Disease Rating Scale)
Effect Of Creatine Monohydrate On Clinical Progression In Patients With Parkinson Disease: A Randomized Clinical Trial
| 効果 | なし |
| 試験方法 | ランダム化比較試験 |
| 試験期間 | 6+ Months |
| 被験者数 | 1741 |
| 性別 | 女性 |
| 年齢 | 45-64, 65+ |
| 体型 | 肥満, 肥満, 平均 |
この研究の注釈：
Participants with early-stage Parkinson’s disease (within 5 years of diagnosis) who also underwent dopaminergic therapy were randomized to receive a placebo or 5 g of creatine twice a day (10 g/day) for a minimum of 5 years. At a preplanned checkpoint, however, the trial was terminated early for futility, as no difference in clinical function (using 5 different scales) was observed between the placebo and creatine groups.