creatine-muscle-damage

この研究の注釈：

Conducted in IronMan athletes.

Confounded with Maltodextrin.

この研究の注釈：

Study conducted in seasoned runners with a personal best in the 2.5-3 hour marathon range, tested after running 30km.

Dosed at 20g creatine per day with 60g maltodextrin (4 doses of 5g creatine monohydrate with 15g carbohydrate) for 5 days prior to event.

Creatine attenuated increases in creatine kinase, PGE2, and TNF-Alpha while abolishing increases in lactate dehydrogenase.

No significant difference noted between groups in marathon time to completion.

この研究の注釈：

In youth, 300 mg/kg/day for 1 week was able to improve performance on a repeated sprint test (35-m sprints, repeated six times with 10-s rests) relative to placebo, but this was not associated with any change in fatigue (assessed via fatigue index) or in biomarkers of oxidative stress, although inflammation was attenuated.

There were unclear effects on muscle damage, since creatine kinase increased while LDH (lactate dehydrogenase, a liver enzyme) decreased.

この研究の注釈：

In youth, 300 mg/kg/day for 1 week was able to improve performance on a repeated sprint test (35-m sprints, repeated six times with 10-s rests) relative to placebo, but this was not associated with any change in fatigue (assessed via fatigue index) or in biomarkers of oxidative stress, although inflammation was attenuated.

There were unclear effects on muscle damage, since creatine kinase increased while LDH (lactate dehydrogenase, a liver enzyme) decreased.

この研究の注釈：

Markers of acute muscle damage decreased.

Improvements in rate of recovery.

Standard loading protocol of 0.03g/kg bodyweight for 5 days (around 21g) and a lower maintenance period (around 5g)

この研究の注釈：

Testing protocol was 15-20 rep squats, 5 sets at 50% 1RM.

Parameters measured indicated that creatine supplementation did not alleviate damage nor enhance recovery from exercise.