| 効果 | 減少 |
| 試験方法 | コホート法 |
| 試験期間 | 不明 |
| 被験者数 | 15 |
| 性別 | 不明 |
この研究の注釈：
4 g/day given to adolescent females suffering from depression was able to significantly reduce depression (56%) over 8 weeks. Supplementation was not compared to placebo, however, which means the number may be inflated, as the benefits from creatine and from the placebo effect are confounded.
Creatine Monohydrate In Resistant Depression: A Preliminary Study
| 効果 | 減少 |
| 試験方法 | コホート法 |
| 試験期間 | 不明 |
| 被験者数 | 8 |
| 性別 | 不明 |
この研究の注釈：
Treated for 4 weeks with 3-5g creatine monohydrate.
Treated for 4 weeks with 3-5g creatine monohydrate.
Depression improved in all subjects, but both subjects with Bipolar disorder experienced worsening symptoms.
A Randomized, Double-Blind Placebo-Controlled Trial Of Oral Creatine Monohydrate Augmentation For Enhanced Response To A Selective Serotonin Reuptake Inhibitor In Women With Major Depressive Disorder
| 効果 | 減少 |
| 試験方法 | 二重盲検法 |
| 試験期間 | 不明 |
| 被験者数 | 52 |
| 性別 | 不明 |
この研究の注釈：
5 g/day as adjunct therapy (alongside SSRIs) showed promise in reducing depression as assessed by the Hamilton Rating Scale for Depression (HRSD) and was safe over the 8 weeks the study lasted.