The Role Of Conjugated Linoleic Acid In Reducing Body Fat And Preventing Holiday Weight Gain
| 効果 | 増加 |
| 試験方法 | 二重盲検法 |
| 試験期間 | 1-6 ヶ月 |
| 被験者数 | 40 |
| 性別 | 男女 |
| 年齢 | 18-29, 30-44 |
| 体型 | 肥満 |
この研究の注釈：
6 months of 3.2g CLA daily was able to reduce body fat by 1+/-2.2kg relative to placebo independent of metabolic rate, physical activity, and diet.
Conjugated Linoleic Acid Modulates Immune Responses In Patients With Mild To Moderately Active Crohn’s Disease
| 効果 | 増加 |
| 試験方法 | コホート法 |
| 試験期間 | 1-6 ヶ月 |
| 被験者数 | 10 |
| 性別 | 不明 |
この研究の注釈：
6g of supplementation (77% CLA by weight; 1:1 ratio of the two main isomers) for 12 weeks noted significant improvements in quality of life () associated with supplementation (pilot study, no placebo group). The benefit seen according to CDAI rating was 13.1% at week 6 and 23.6% at 12 weeks with the authors suggesting that it may not be clinically significant.
6g of supplementation (77% CLA by weight; 1:1 ratio of the two main isomers) for 12 weeks noted significant improvements in quality of life () associated with supplementation (pilot study, no placebo group). The benefit seen according to CDAI rating was 13.1% at week 6 and 23.6% at 12 weeks with the authors suggesting that it may not be clinically significant.
Secretion of IL-2 increased from isolated CD4+ and CD8+ lymphocytes, while serum IL-6 was higher after 12 weeks. IL-8, IL-1β, IL-10, TNF-α, or IL-12p70 were all unaffected, and lymphocyte secretion of TNF-α and IFNy was reduced.