| 効果 | 増加 |
| 試験方法 | 二重盲検法 |
| 試験期間 | 不明 |
| 被験者数 | 60 |
| 性別 | 不明 |
この研究の注釈：
No effects on AST or ALT noted after 3.5g CLA of either mixed isomers, or either the c9t11 or t10c12 isomers in isolation. One group also took 200mg vitamin E and another group 12.5mg Rofecoxib, over 6 weeks in otherwise healthy persons.
Dietary Supplementation With 11trans- And 12trans-18:1 And Oxidative Stress In Humans
| 効果 | 増加 |
| 試験方法 | 二重盲検法 |
| 試験期間 | 不明 |
| 被験者数 | 24 |
| 性別 | 不明 |
この研究の注釈：
6g of trans fatty acids, of which CLA comprised some, was able to increase urinary 8-isoPGF(2)a; a biomarker for lipid peroxidation induced by free radicals. Markers of DNA damage did not change.
A Diet Rich In Conjugated Linoleic Acid And Butter Increases Lipid Peroxidation But Does Not Affect Atherosclerotic, Inflammatory, Or Diabetic Risk Markers In Healthy Young Men
| 効果 | 増加 |
| 試験方法 | コホート法 |
| 試験期間 | 不明 |
| 被験者数 | 38 |
| 性別 | 男性 |
| 年齢 | 18-29 |
| 体型 | 肥満 |
この研究の注釈：
Butter, at 115g per day, was compared against butter (incorporated into foods). One was enriched with 5.5g CLA (39.4% c9t11, 38.5% t10c12) and the other had insignificant CLA levels, instead having lesser fatty acids and the subjects having to seek out additional fatty acids daily. Dietitian intervention had minimized differences, but some existed between group (CLA group reporting slightly higher caloric and PUFA intake)
Butter, at 115g per day, was compared against butter (incorporated into foods). One was enriched with 5.5g CLA (39.4% c9t11, 38.5% t10c12) and the other had insignificant CLA levels, instead having lesser fatty acids and the subjects having to seek out additional fatty acids daily. Dietitian intervention had minimized differences, but some existed between group (CLA group reporting slightly higher caloric and PUFA intake)
Urine 8-iso-PGF2α increased to 183% of the control group after CLA ingestion, an in vivo marker of lipid peroxidation. No other changes were noted.