IGF-I, IgA, And IgG Responses To Bovine Colostrum Supplementation During Training
効果 | なし |
試験方法 | 二重盲検法 |
試験期間 | 2-4 週間 |
被験者数 | 30 |
性別 | 男女 |
年齢 | 18-29 |
体型 | 平均 |
Supplementation of 20g colostrum (4.8g immunoglobulins and 74mcg IGF-1) for two weeks in healthy adults is able to increase IGF-1 concentrations by 17%, but this does not appear to be related to oral consumption of IGF-1 in the product (as it is hydrolyzed).
Salivary, but not serum, IgA was increased 33% and IgG was not affected despite oral ingestion of 4.5g IgG (0.3g IgA).
Effect Of Bovine Colostrum Supplementation On Respiratory Tract Mucosal Defenses In Swimmers
効果 | なし |
試験方法 | 二重盲検法 |
試験期間 | 1-6 ヶ月 |
被験者数 | 43 |
性別 | 男女 |
年齢 | 18-29 |
体型 | トレーニング中, トレーニングしてない, 平均 |
Supplementation of colostrum (50g taken in two doses daily; about 3% IgG) in both athletes and sedentary persons for 10 weeks failed to influence both salivary and serum concentrations of IgA, IgM, and IgG; while it appeared that there were less upper respiratory tract symptoms in the latter half of the study with colostrum this did not reach significance.
Bovine Colostrum Supplementation’s Lack Of Effect On Immune Variables During Short-term Intense Exercise In Well-trained Athletes
効果 | なし |
試験方法 | 二重盲検法 |
試験期間 | 1-2 週間 |
被験者数 | 9 |
性別 | 男性 |
年齢 | 18-29 |
体型 | トレーニング中, 平均 |
Supplementation of colostrum at 25g daily (two doses) with a high IgG content (65g/L) for ten days in which the last two days were a glycogen depletion trial followed by an endurance trial (90m at 50% Wmax) failed to alter performance during the glycogen depletion trial (anaerobic), failed to alter immune cell changes during exercise, immunoglobulins in serum, or any measured interleukin or cytokine relative to placebo (skim milk).
Modulation Of Human Humoral Immune Response Through Orally Administered Bovine Colostrum
効果 | 増加 |
試験方法 | 二重盲検法 |
試験期間 | 1-7 Days |
被験者数 | 18 |
性別 | 男女 |
年齢 | 18-29, 30-44, 45-64 |
In otherwise healthy adult volunteers given 100mL of a colostrum beverage (Bioenervi) for one week where vaccination capsules were also ingested thrice, supplementation appeared to augment the vaccine induced elevations of IgA and IgG, but not IgM, specific to the vaccine despite the total immunoglobulin secreting cells not being altered nor their receptors.