Oral Citrulline Does Not Affect Whole Body Protein Metabolism In Healthy Human Volunteers: Results Of A Prospective, Randomized, Double-blind, Cross-over Study

この研究の注釈:

0.18g/kg citrulline supplementation daily for a week (without exercise) failed to significantly influence plasma IGF-1 or insulin and did not affect muscle protein synthesis rates. A 13% decrease in glutamine concentrations in serum was noted.


L-citrulline-malate Influence Over Branched Chain Amino Acid Utilization During Exercise

この研究の注釈:

Supplementation of 6g citrulline prior to a prolonged exercise test was associated with an increase in urea (27.1-30.4%) and nitrite (indicative of nitric oxide) and appeared to attenuate the rise in urate. Growth hormone increased 66.8% after exercise


Dose-ranging Effects Of Citrulline Administration On Plasma Amino Acids And Hormonal Patterns In Healthy Subjects: The Citrudose Pharmacokinetic Study

この研究の注釈:

Graded supplementation of citrulline between 2g and 15g in otherwise healthy adults at rest failed to influence measured hormonal parameters and safety testing failed to find a reduction in blood pressure at rest.


L-citrulline Reduces Time To Exhaustion And Insulin Response To A Graded Exercise Test

この研究の注釈:

In an incline walking test until failure in otherwise healthy persons, 3 or 9g citrulline (acutely or over 24 hours, respectively) appeared to actually reduce time to exhaustion (0.8%, a clinically irrelevant degree) and suppressed the exercise-induced increase in insulin. Other biomarkers tested were unaltered, although heart rate trended to decrease with 3g citrulline