Short-term Effects Of L-citrulline Supplementation On Arterial Stiffness In Middle-aged Men
| 効果 | なし |
| 試験方法 | 二重盲検法 |
| 試験期間 | 1-7 日 |
| 被験者数 | 15 |
| 性別 | 男性 |
| 年齢 | 45-64 |
| 体型 | 肥満 |
5,600mg of citrulline daily for 7 days in otherwise healthy middle aged men was able to improve blood flow secondary to nitric oxide, but did not influence blood pressure per se. The improvement in blood flow was correlated with the serum increases in arginine.
Effect Of L-arginine Or L-citrulline Oral Supplementation On Blood Pressure And Right Ventricular Function In Heart Failure Patients With Preserved Ejection Fraction
| 効果 | 減少 |
| 試験方法 | コホート法 |
| 試験期間 | 1-6 ヶ月 |
| 被験者数 | 30 |
| 性別 | 男女 |
| 年齢 | 45-64, 65+ |
| 体型 | 肥満 |
In heart failure patients with preserved ejection fraction, 3g of supplemental citrulline daily was able to promote cardiac function and reduce blood pressure. Arginine at 8g was equally effective, and this study lacked a placebo control.
Oral L-citrulline Supplementation Attenuates Blood Pressure Response To Cold Pressor Test In Young Men
| 効果 | 減少 |
| 試験方法 | 二重盲検法 |
| 試験期間 | 2-4 週間 |
| 被験者数 | 17 |
| 性別 | 男性 |
| 年齢 | 18-29, 30-44 |
| 体型 | 平均 |
In youth subject to a cold pressor test (which acutely increases blood pressure) noted that 4 weeks of citrulline supplementation at two daily doses of 3g (6g total) was able to attenuate the rise in systolic but not diastolic blood pressure relative to baseline.