A standardized Withania somnifera extract significantly reduces stress-related parameters in chronically stressed humans: a double-blind, randomized, placebo-controlled study

効果 減少
試験方法 二重盲検法
試験期間 1-6 ヶ月
被験者数 98
性別 男女
年齢 18-29, 30-44, 45-64
この研究の注釈：

Chronically stressed people taking an ashwagandha extract for 60 days saw improvements with regard to anxiety, well-being, and serum health parameters. Cortisol decreased (by 14.5% for 125 mg/day, 24.2% for 250 mg/day, and 30.5% for 500 mg/day), as did LDL-C (by 17.4% for 500 mg/day) and VLDL-C (by 23.9% for 500 mg/day), while HDL-C increased (by 17.3% for 500 mg/day).

研究の資金源に関する問題点：

Authors are involved with companies that produce ashwagandha supplements, Nutragenesis and Natreon

A Prospective, Randomized Double-blind, Placebo-controlled Study Of Safety And Efficacy Of A High-concentration Full-spectrum Extract Of Ashwagandha Root In Reducing Stress And Anxiety In Adults

効果 減少
試験方法 二重盲検法
試験期間 1-6 ヶ月
被験者数 64
性別 男女
年齢 18-29, 30-44, 45-64
体型 平均
この研究の注釈：

300 mg of an ashwagandha extract (“full spectrum”) for 60 days in persons with chronic mental stress was able to improve all tested parameters and reduced serum cortisol by 27.9%.

Withania Somnifera Improves Semen Quality In Stress-Related Male Fertility

効果 減少
試験方法 コホート法
試験期間 1-6 ヶ月
被験者数 60
性別 男性
年齢 18-29, 30-44
体型 平均
この研究の注釈：

Supplementation of 5 g of the root powder daily with skin milk for 3 months in infertile men with otherwise normal sperm morphology was able to increase sperm concentration and motility with more efficacy in men who were highly stressed (rather than heavy smokers or those who were neither) and was able to increase testosterone (10–22%) and reduce cortisol (11–32% AUC; 36-48% when measured at 4 p.m.) with similar favoring of stressed men.