Long-term Low-dose Dehydroepiandrosterone Oral Supplementation In Early And Late Postmenopausal Women Modulates Endocrine Parameters And Synthesis Of Neuroactive Steroids

効果 増加
試験方法 コホート法
試験期間 6+ ヶ月
被験者数 20
性別 女性
年齢 45-64
体型 肥満
この研究の注釈：

25mg of DHEA over 12 months was able to increase all steroid hormones in the serum, including the neurosteroids allopregnanolone and beta-endorphin. SHBG also decreased alongside cortisol, and overall menopausal symptoms in these women was decreased.

Effects Of Dehydroepiandrosterone (DHEA) Supplementation On Hormonal, Metabolic And Behavioral Status In Patients With Hypoadrenalism

効果 なし
試験方法 コホート法
試験期間 1-6 ヶ月
被験者数 20
性別 男女
年齢 30-44, 45-64
体型 肥満
この研究の注釈：

DHEA at 50mg for 4 months was unable to influence serum testosterone levels in men, while it increased testosterone levels only in women with low circulating androgens. SHBG dropped in men and women, and DHEA-S in serum increased in both groups.

No effects on carbohydate metabolism or insulin sensitivity were seen. Fat mass decreased, no effects on well being and quality of life were seen.

Patients were hypoadrenics.