効果 | なし |
試験方法 | 二重盲検法 |
試験期間 | 1-6 ヶ月 |
被験者数 | 34 |
性別 | 男性 |
年齢 | 18-29 |
体型 | 平均 |
Supplementation of 60g colostrum daily for eight weeks in otherwise healthy sedentary persons (at least three months of somewhat routine activity) subject to a weight lifting regimen (four times weekly) during the experiment noted that, relative to whey protein, that increases in muscle mass were seen in both groups yet comparable; an exception was total limb circumference and cross sectional area, but the increase in colostrum relative to whey was thought to be due to lower baseline values in the colostrum group.
Dose Effects Of Oral Bovine Colostrum On Physical Work Capacity In Cyclists
効果 | なし |
試験方法 | 二重盲検法 |
試験期間 | 1-6 ヶ月 |
被験者数 | 28 |
性別 | 男性 |
年齢 | 18-29, 30-44 |
体型 | トレーニング中, 平均 |
Supplementation of either 60g whey protein, 60g colostrum, or a combination of 20g colostrum with 40g whey, in elite cyclists over the course of eight weeks noted that performance on a weighted cycling test (similar to Wingate) failed to have any difference between groups (despite all groups improving by about 4% relative to baseline) although in a 2 hour endurance test there was an improvement of 132s and 158s in the colostrum groups (difference not significant) which were both greater than the whey only group at 37s.
Randomised Controlled Trial Of Colostrum To Improve Intestinal Function In Patients With Short Bowel Syndrome
効果 | なし |
試験方法 | 二重盲検法 |
試験期間 | 2-4 週間 |
被験者数 | 8 |
性別 | 男女 |
年齢 | 18-29, 30-44 |
体型 | Underweight |
In patients with short bowel syndrome, supplementation of colostrum (250mL of a beverage containing 26.5g protein; control of skim milk and protein) for four weeks failed to outperform placebo protein in improving nutritive status and protein absorption and underperformed for increasing weight and lean mass. Power output (assessed by handgrip strength) was not different between groups but increased with protein in general.
Meal-induced GLP-2 secretion was not different between groups.
Bovine Colostrum Supplementation During Running Training Increases Intestinal Permeability
効果 | なし |
試験方法 | 二重盲検法 |
試験期間 | 1-6 ヶ月 |
被験者数 | 30 |
性別 | 男性 |
年齢 | 18-29 |
体型 | トレーニング中, 平均 |
Supplementation of 60g bovine colostrum (immunoglobulin content not disclosed) daily for eight weeks alongside thrice weekly aerobic training noted that, when subject to a 30 minute run to exhaustion, that colostrum was associated with an increase in intestinal permeability without any overt gastointestinal side effects.
No performance parameter was increased with supplementation.
Funded by Numico, producer of the colostrum produced used
The Effect Of Bovine Colostrum Supplementation On Exercise Performance In Elite Field Hockey Players
効果 | 増加 |
試験方法 | 二重盲検法 |
試験期間 | 1-6 ヶ月 |
被験者数 | 35 |
性別 | 男女 |
年齢 | 18-29 |
体型 | トレーニング中, 平均 |
Eight weeks supplementation of colostrum powder at 60g (three doses of 20g) in elite field hockey players during the beginning of their competitive seasons noted that, relative to the placebo (whey protein), colostrum failed to improve anaerobic cardiovascular exercise (sprints and suicide runs) and did not influence power output.
Lean mass increased with colostrum relative to baseline, but was similar to the increase seen with whey protein.
Effect Of Bovine Colostrum Supplementation On Respiratory Tract Mucosal Defenses In Swimmers
効果 | なし |
試験方法 | 二重盲検法 |
試験期間 | 1-6 ヶ月 |
被験者数 | 43 |
性別 | 男女 |
年齢 | 18-29 |
体型 | トレーニング中, トレーニングしてない, 平均 |
Supplementation of colostrum (50g taken in two doses daily; about 3% IgG) in both athletes and sedentary persons for 10 weeks failed to influence both salivary and serum concentrations of IgA, IgM, and IgG; while it appeared that there were less upper respiratory tract symptoms in the latter half of the study with colostrum this did not reach significance.
The Effect Of Bovine Colostrum Supplementation On Salivary IgA In Distance Runners
効果 | なし |
試験方法 | 二重盲検法 |
試験期間 | 1-6 ヶ月 |
被験者数 | 35 |
性別 | 男女 |
年齢 | 30-44, 45-64 |
体型 | トレーニング中, 平均 |
In long distance runners, supplementation of colostrum powder at 26g daily for 14 weeks (placebo of skin milk) noted an increase in salivary IgA of 79% (relative to a 12% increase seen with placebo) noted at 12 weeks (but not 4 nor 8).
The Effects Of Bovine Colostrum Supplementation On Body Composition And Exercise Performance In Active Men And Women
効果 | なし |
試験方法 | 二重盲検法 |
試験期間 | 1-6 ヶ月 |
被験者数 | 20 |
性別 | 男女 |
年齢 | 18-29, 30-44 |
Supplementation of 20g colostrum daily for eight weeks in active subjects, relative to the placebo of whey protein (20g), appeared to have a slight increase in lean mass (2.3%) without any changes in weight due to nonsignificant decreases in fat mass; whey protein did not have any significant changes relative to baseline. Measurements via DEXA.
Performance parameters including treadmill time to exhaustion, power output, and muscular endurance did not change.
Effect Of Bovine Colostrum On Anaerobic Exercise Performance And Plasma Insulin-like Growth Factor I
効果 | 増加 |
試験方法 | 二重盲検法 |
試験期間 | 1-6 ヶ月 |
被験者数 | 51 |
性別 | 男性 |
年齢 | 18-29, 30-44 |
体型 | 平均 |
In lightly active men given colostrum at 60g daily conferring 120mcg IGF-1 (placebo of whey protein at the same dose) daily for eight weeks alongside a six time weekly training protocol noted that colostrum failed to improve any measurement of power output relative to whey protein.
Treatment Of Severe Diarrhea Caused By Cryptosporidium Parvum With Oral Bovine Immunoglobulin Concentrate In Patients With AIDS
効果 | なし |
試験方法 | コホート法 |
試験期間 | 2-4 週間 |
被験者数 | 24 |
性別 | 男女 |
年齢 | 30-44 |
体型 | 平均 |
21 days supplementation of colostrum in persons with HIV/AIDS associated diarrhea (no placebo control) noted significant reductions in stool weight and frequency associated with powdered colostrum () but not encapsulated colostrum (), with the reduction seen with powdered colostrum being from 6.6 defecations daily down to 5.4.
Patients not infected by Cryptosporidium parvum did not experience benefit from powdered colostrum.
Oral Bovine Colostrum Supplementation Enhances Buffer Capacity But Not Rowing Performance In Elite Female Rowers
効果 | なし |
試験方法 | 二重盲検法 |
試験期間 | 1-6 ヶ月 |
被験者数 | 13 |
性別 | 女性 |
年齢 | 18-29 |
体型 | トレーニング中, 平均 |
60g colostrum daily in elite female rowers daily for nine weeks, relative to whey protein as control, appeared to reliably increase blood buffering capacity (assessed by the relationship between lactate and pH) but this buffering capacity was not associated with performance on rowing tests and the actual performance on rowing tests was not affected by supplementation.
Bovine Colostrum Supplementation During Endurance Running Training Improves Recovery, But Not Performance
効果 | なし |
試験方法 | 二重盲検法 |
試験期間 | 1-6 ヶ月 |
被験者数 | 30 |
性別 | 男性 |
年齢 | 18-29, 30-44 |
体型 | 平均 |
Supplementation of colostrum for eight weeks (60g, containing 2mg/kg IGF-1) in otherwise healthy mildly active adult males with whey protein as placebo noted that colostrum failed to influence performance on a treadmill running test (approximately 30 minutes) or biochemical parameters in the blood. Plasma IGF-1 was not different between groups.
Effect Of Bovine Colostrum-based Food Supplement In The Treatment Of HIV-associated Diarrhea In Northern Uganda: A Randomized Controlled Trial
効果 | 増加 |
試験方法 | 二重盲検法 |
試験期間 | 2-4 週間 |
被験者数 | 97 |
性別 | 男女 |
年齢 | 18-29, 30-44, 45-64 |
体型 | 平均, Underweight |
50g of a colostrum containing porridge (twice daily) for four weeks to persons with HIV-associated diarrhea for four weeks (and followed up for an additional five) significantly reduced stool frequency 79% (58% in controls given standard anti-diarrhea therapy) and increased CD4+ lymphocytes 14% despite a 12% decrease in control. Fatigue was reported to be reduced by 85% relative to baseline, greater than the 43% reduction seen with placebo.